Bialaphos (CAS 35597-43-4) Supplier Information and Product Details

Bialaphos is a natural herbicide produced by the bacteria Streptomyces hygroscopicus and Streptomyces viridochromogenes. It is a tripeptide comprising one L-phosphinothricyl and two L-alanyl units joined in sequence. Bialaphos is readily soluble in water and insoluble in organic solvents such as acetone, ethanol, benzene, and hexane.

In plants, bialaphos is metabolized to L-glufosinate, which inhibits the enzyme glutamine synthetase (GS). This leads to rapid accumulation of ammonium ions and inhibition of photosynthesis, resulting in plant death. Bialaphos was launched as a non-selective contact herbicide in 1984.

Frequently Asked Questions

Q: What is the primary use of Bialaphos?

A: Bialaphos is primarily used as a natural herbicide. It is metabolized in plants to L-glufosinate, which inhibits glutamine synthetase, leading to plant death.

Q: How is Bialaphos produced?

A: Bialaphos is a natural product formed during the fermentation of bacteria, specifically Streptomyces hygroscopicus and Streptomyces viridochromogenes.

Q: What are the safety considerations when handling Bialaphos?

A: Bialaphos is classified as harmful (Xn). Safety precautions include wearing protective clothing and avoiding contact with skin and eyes. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

Q: How is Bialaphos metabolized?

A: When administered to mice, the major metabolite of Bialaphos is 2-amino-4-(hydroxy-methyl-phosphinoyl)butyric acid, which is excreted in feces and urine.