Capastat Sulfate (CAS 1405-37-4) Suppliers and Product Information

Capastat sulfate is a polypeptide antibiotic isolated from Streptomyces capreolus. It is used as an antibacterial and tuberculostatic agent, effective against Mycobacterium tuberculosis and other Gram-positive and Gram-negative organisms. The compound acts by binding to the 23S ribosomal subunit, disrupting protein synthesis.

Frequently Asked Questions about Capastat Sulfate

What is the main use of Capastat sulfate?

Capastat sulfate is primarily used as an antitubercular agent, especially for treating tuberculosis caused by streptomycin-resistant Mycobacterium or for patients who experience adverse side effects from streptomycin.

How does Capastat sulfate work?

Capastat sulfate is thought to inhibit protein synthesis by disrupting normal ribosomal functions. It binds to the 23S ribosomal subunit, interfering with bacterial protein production.

Is Capastat sulfate effective against drug-resistant tuberculosis?

Yes, Capastat sulfate shows no cross-resistance with streptomycin, making it useful for treating streptomycin-resistant Mycobacterium tuberculosis infections.

What are the storage requirements for Capastat sulfate?

Capastat sulfate should be stored in a freezer under -20°C and kept sealed in dry conditions to maintain its stability.