Carmofur (CAS 61422-45-5) Suppliers and Product Information

Carmofur is a cytostatic derivative of fluorouracil used as an antineoplastic agent. It acts as an inhibitor of acid ceramidase with an IC50 of 79 nM for the rat enzyme. Carmofur reduces acid ceramidase activity in a dose- and time-dependent manner and induces intracellular accumulation of various ceramide species in cancer cells. It has been used in research to study its effects on glucosylsphingosine production and ceramide hydrolysis.

Frequently Asked Questions about Carmofur

Q: What is the primary use of Carmofur?

A: Carmofur is primarily used as an antineoplastic agent. It is a cytostatic derivative of fluorouracil and acts as an inhibitor of acid ceramidase, making it useful in cancer research and potentially in cancer treatment.

Q: How should Carmofur be stored?

A: Carmofur should be stored long-term at 2-8°C to maintain its stability.

Q: What is the typical purity of commercially available Carmofur?

A: The purity of commercially available Carmofur typically ranges from ≥97% to ≥99%, depending on the supplier.

Q: Is Carmofur considered hazardous?

A: Yes, Carmofur is classified as a hazardous material. It falls under UN hazard class 6.1 and has the UN number UN2811.