Demecarium Bromide (CAS 56-94-0) Suppliers and Product Information

Demecarium bromide is a disymmetrical compound containing two ammonium and two carbamate groups. It functions as a reversible cholinesterase inhibitor with a long duration of action. Its primary uses include constricting pupils, elevating intraocular pressure in glaucoma treatment, and alleviating atropine mydriasis. In veterinary medicine, it is used to treat elevated intraocular pressure associated with primary glaucoma.

Frequently Asked Questions about Demecarium Bromide

Q: What is the main use of Demecarium Bromide?

A: Demecarium Bromide is primarily used to treat chronic open-angle glaucoma. It helps reduce intraocular pressure by causing constriction of the iris sphincter muscle and ciliary muscle, which facilitates the outflow of aqueous humor.

Q: How does Demecarium Bromide work?

A: Demecarium Bromide is an acetylcholinesterase inhibitor. It works by inhibiting the enzyme that breaks down acetylcholine, leading to increased acetylcholine levels. This results in increased stimulation of cholinergic receptors, causing pupil constriction and improved aqueous humor outflow.

Q: Are there any other applications for Demecarium Bromide?

A: Besides its use in glaucoma treatment, Demecarium Bromide has been investigated as a potential anticancer agent for pancreatic islet cells. It is also used in veterinary medicine to treat elevated intraocular pressure associated with primary glaucoma in animals, particularly dogs.

Q: What are the advantages of Demecarium Bromide over other similar drugs?

A: Demecarium Bromide has a longer duration of action compared to other cholinesterase inhibitors. In veterinary use, it has the advantage of requiring only once or twice daily dosing, which can improve treatment compliance.