Orlistat (CAS 96829-58-2) Suppliers and Product Information

Orlistat is a potent lipase inhibitor derived from lipstatin, naturally produced by Streptomyces toxytricini. It acts as an antiobesity agent by inhibiting pancreatic lipase, reducing the absorption of dietary fat. Orlistat also shows potential as a fatty acid synthase inhibitor and may have applications in cancer research.

Frequently Asked Questions about Orlistat

Q: What is the primary use of Orlistat?

A: Orlistat is primarily used as an antiobesity agent. It works by inhibiting pancreatic lipase, which reduces the absorption of dietary fat, contributing to weight loss.

Q: How does Orlistat work in the body?

A: Orlistat acts locally in the gastrointestinal tract to inhibit lipase enzymes. This inhibition prevents the breakdown and absorption of approximately one-third of dietary fat, leading to reduced calorie intake.

Q: Are there any potential drug interactions with Orlistat?

A: Yes, Orlistat may interact with several medications. It can potentially reduce the absorption of fat-soluble vitamins and certain drugs such as amiodarone, anticoagulants, antiepileptics, some antivirals, ciclosporin, and thyroid hormones. It's important to consult a healthcare provider for personalized advice.

Q: What are the storage requirements for Orlistat?

A: Orlistat should be stored at 4°C (39.2°F) to maintain its stability and effectiveness.