Disopyramid Phosphate (CAS 22059-60-5) Suppliers and Product Information

Disopyramide Phosphate is an antiarrhythmic (class IA) sodium channel blocker. It is used clinically in the treatment of refractory life-threatening ventricular tachyarrhythmias. The drug has a half-life of 6-7 hours in humans and is approximately 50% bound to plasma proteins. More than 50% is excreted unchanged in the urine.

Frequently Asked Questions

Q: What are the main uses of Disopyramide Phosphate?

A: Disopyramide Phosphate is primarily used as an antiarrhythmic agent for treating cardiac arrhythmias. It is specifically used in the treatment of refractory life-threatening ventricular tachyarrhythmias.

Q: What are the common side effects of Disopyramide Phosphate?

A: Common side effects of Disopyramide Phosphate include dry mouth, constipation, urinary retention, and other cholinergic blocking actions. These effects are due to its structural similarity to anticholinergic drugs.

Q: How is Disopyramide Phosphate administered?

A: Disopyramide Phosphate can be administered both orally and intravenously. Oral administration produces peak plasma levels within 2 hours.

Q: Are there any special considerations for patients with renal insufficiency?

A: Yes, patients with renal insufficiency should be monitored carefully for evidence of overdose when taking Disopyramide Phosphate. This is because more than 50% of the drug is excreted unchanged in the urine.