Product Name | Mildronate (Meldonium) |
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CAS Number | 76144-81-5 |
Molecular Formula | C6H14N2O2 |
Molecular Weight | 146.19 |
EINECS | 682-135-0 |
Appearance | White to Off-White Solid |
Melting Point | 85-90°C |
Solubility | Slightly soluble in Methanol and Water |
Storage | Refrigerator |
Stability | Hygroscopic |
Mildronate, also known as Meldonium, is a cardiac and neuroprotective drug. It is used to treat angina, myocardial infarction, and chronic heart failure. The compound is a structural ***og of carnitine and acts by inhibiting carnitine-dependent fatty acid oxidation. Mildronate has shown beneficial effects on cerebral circulation disorders and central nervous system functions.
Q: What is the main mechanism of action of Mildronate?
A: Mildronate's main mechanism of action is based on carnitine biosynthesis inhibition. This prevents the accumulation of cytotoxic intermediate products of fatty acid beta-oxidation in ischemic tissues and blocks this highly oxygen-consuming process.
Q: What are the clinical applications of Mildronate?
A: Mildronate is used for the treatment of heart ischemia and its consequences. It is also used in neurological clinics for the treatment of brain circulation disorders. The drug has shown efficacy in improving patients' mood, motor function, and reducing symptoms like asthenia, dizziness, and nausea.
Q: Are there any side effects associated with Mildronate use?
A: Possible side effects of Mildronate treatment include allergic reactions (redness, itchy skin, urticaria, rash, angioedema), weakness, headache, discomfort in the epigastrium, dyspepsia, tachycardia, and changes in blood pressure. However, these side effects are reported to be rare.
Q: Is Mildronate banned for athletes?
A: Yes, Mildronate (Meldonium) was added to the World Anti-Doping Agency (WADA) list of banned substances on January 1, 2016, due to evidence of its use by athletes with the intention of enhancing performance.
Company Name | Contact Information | Product Details |
---|---|---|
Hefei TNJ Chemical Industry Co., Ltd. | Tel: 0551-65418684, 86-18949823763 | MILDRONATE (CAS 76144-81-5) |
Wuhan senwayer century chemical Co., Ltd. | Tel: 86-27-86652399, 86-13627115097 | Mildronate (CAS 76144-81-5), Purity: 99% HPLC, Package: 1KG 280USD |
Sinoway Industrial co., ltd. | Tel: 0592-5800732, 86-13806035118 | Mildronate (CAS 76144-81-5), Purity: 99% up EP, Package: 25Kg Bag |
Hangzhou ICH Biofarm Co., Ltd. | Tel: 86-0571-28186870, 86-13073685410 | Meldonium (CAS 76144-81-5), Purity: 99.0% min, Package: 1kg, 5kg, 10kg |
Guangzhou Tengyue Chemical Co., Ltd. | Tel: 86-18148706580, 86-18826483838 | Mildronate (CAS 76144-81-5), Purity: 99%, Package: 1kg 350USD, 25kg 220USD |
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