Gestrinone (CAS 16320-04-0) Suppliers and Product Information

Gestrinone is a synthetic steroid with antiprogesterone and antiestrogenic activities. It acts centrally on the hypothalamic-pituitary system and is used in the treatment of endometriosis and uterine leiomyomas. The compound inhibits gonadotropin release and has weak inhibitory effects on its synthesis. It also possesses anti-estrogen activity.

Frequently Asked Questions about Gestrinone

Q: What are the main uses of Gestrinone?

A: Gestrinone is primarily used in the treatment of endometriosis and uterine leiomyomas. It has also been investigated for use in emergency contraception.

Q: What are the common side effects of Gestrinone?

A: Common side effects include nausea, headache, mood changes, rash, hot flushes, weight gain, and discomfort in the joints and muscles. In some cases, there may be evidence of masculinization.

Q: How does Gestrinone work?

A: Gestrinone primarily acts on the hypothalamic-pituitary axis, inhibiting gonadotropin release. It also has anti-estrogenic activity and may inhibit implantation by acting on the endometrium.

Q: What is the recommended storage for Gestrinone?

A: Gestrinone should be stored at -20°C in a freezer to maintain its stability.