Property | Value |
---|---|
Product Name | Sertaconazole nitrate |
CAS Number | 99592-39-9 |
Molecular Formula | C20H15Cl3N2OS · HNO3 |
Molecular Weight | 500.78 g/mol |
Synonyms | Dermofix, Ertaczo, Zalain |
Appearance | White to beige powder |
Melting Point | 158-160°C |
Storage Temperature | -20°C |
Solubility | Soluble in DMSO (20mg/mL clear) |
pKa | 7.26 at 25°C |
Sertaconazole nitrate is a broad-spectrum imidazole antifungal agent used in topical formulations for treating cutaneous infections. It works by inhibiting ergosterol synthesis and interfering with fungal cell membrane permeability. An oral formulation is being investigated for bucco-pharyngeal fungal infections.
The compound is classified as a WGK 3 substance in Germany, indicating a severe hazard to waters. Proper safety precautions should be taken when handling this chemical.
Q: What is the main use of Sertaconazole nitrate?
A: Sertaconazole nitrate is primarily used as a broad-spectrum topical antifungal agent for treating cutaneous infections. It is also being investigated in oral form for bucco-pharyngeal fungal infections.
Q: How does Sertaconazole nitrate work?
A: Sertaconazole nitrate works by inhibiting ergosterol synthesis, which is an essential component of fungal cell walls. It also interferes with the permeability of fungus cell membranes.
Q: Is Sertaconazole nitrate available in different formulations?
A: Yes, Sertaconazole nitrate is available in topical formulations for skin infections. An oral formulation is currently under investigation for treating bucco-pharyngeal fungal infections.
Q: Are there any safety concerns when handling Sertaconazole nitrate?
A: Yes, Sertaconazole nitrate is classified as WGK 3 in Germany, indicating a severe hazard to waters. Proper safety precautions should be taken when handling this chemical.
Company Name | Contact Information | Product Details |
---|---|---|
Capot Chemical Co., Ltd. | Tel: 86 571-85586718 Mobile: 86 13336195806 Email: [email protected] |
Purity: NLT 98% Package: 1G, 1KG, 100KG |
Henan Tianfu Chemical Co., Ltd. | Tel: 86 0371-55170693 Mobile: 86 19937530512 |
Purity: 99% Package: 25KG, 5KG, 1KG |
Nanjing ChemLin Chemical Industry Co., Ltd. | Tel: 86 025-83697070 | Purity: 98% Package: g, Kg |
Career Henan Chemical Co. | Tel: 86 0371-86658258 Mobile: 86 13203830695 |
Purity: 99% Package: 1kg |
BOC Sciences | Tel: 1 631-485-4226 | Purity: ≥98% Package: 200mg Note: Custom synthesis available |
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