Property | Value |
---|---|
Chemical Name | Calcium folinate pentahydrate |
CAS Number | 6035-45-6 |
Molecular Formula | C20H21CaN7O7·5H2O |
Molecular Weight | 601.58 |
Melting Point | >300°C |
Optical Rotation | 14.9° (c=1, in H2O) |
Physical Form | Solid |
Color | Yellow-white to yellow |
Solubility | Insoluble in DMSO and EtOH, 15.04 mg/mL in H2O with gentle warming |
Calcium folinate is the calcium salt of folinic acid, an adjuvant used in chemotherapy involving methotrexate. It supplies cells with tetrahydrofolate and diminishes methotrexate toxicity without abolishing the antitumor effects. It is used as an antianemic agent and is also known by the brand name Wellcovorin.
Q: What is the main use of calcium folinate?
A: Calcium folinate is primarily used as an adjuvant in chemotherapy involving methotrexate. It helps reduce methotrexate toxicity while maintaining its antitumor effects. It is also used as an antianemic agent.
Q: How should calcium folinate be stored?
A: Calcium folinate should be stored long-term in a cool, dry place. It is recommended to keep it in dark conditions at a temperature between 2-8°C.
Q: Is calcium folinate hazardous?
A: While not classified as highly hazardous, calcium folinate carries some risks. It has hazard statements H315, H319, and H335, indicating it can cause skin and eye irritation and may cause respiratory irritation. Proper handling precautions should be taken.
Company Name | Contact | Product Details |
---|---|---|
Wuhan Fortuna Chemical Co., Ltd. | Tel: 86 027 59207850 | Purity: 95-105%, Package: 1Kg Bag |
Hebei Hongtan Biotechnology Co., Ltd. | Tel: 86 17331935328 | Purity: 99%, Package: 1kg, Price: $30.00 USD |
Career Henan Chemical Co. | Tel: 86 0371 86658258 | Purity: 98%, Package: 1kg, Price: 1USD |
Chongqing Chemdad Co., Ltd. | Tel: 86 023 6139 8061 | Purity: 98%, Package: 1kg, 2kg, 5kg, 10kg, 25kg |
CONIER CHEM AND PHARMA LIMITED | Tel: 8618523575427 | Purity: 99%, Package: 1kg |
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