Property | Value |
---|---|
Product Name | 1-(2,6-Dimethylphenoxy)-2-propanamine |
CAS Number | 31828-71-4 |
Molecular Formula | C11H17NO |
Molecular Weight | 179.26 |
Melting Point | 203-205 °C |
Boiling Point | 271.5±28.0 °C (Predicted) |
Density | 0.979±0.06 g/cm3 (Predicted) |
Appearance | White powder |
1-(2,6-Dimethylphenoxy)-2-propanamine, also known as Mexiletine, is an antiarrhythmic agent with properties similar to lidocaine and tocainide. It is used for treating ventricular arrhythmias, including extrasystole, tachycardia, and fibrillation. The compound is effective both parenterally and orally.
Mexiletine has a large distribution volume, requiring a high initial dose. It is also being investigated for use in treating amyotrophic lateral sclerosis and as an ***gesic. The compound belongs to BCS Class 1 and has a pKa of 9.14.
Q: What are the main uses of 1-(2,6-Dimethylphenoxy)-2-propanamine?
A: The main uses of 1-(2,6-Dimethylphenoxy)-2-propanamine, also known as Mexiletine, include: - Treatment of ventricular arrhythmias (extrasystole, tachycardia, and fibrillation) - Potential use in treating amyotrophic lateral sclerosis - Analgesic properties for pain management
Q: What are the side effects of Mexiletine?
A: Common side effects of Mexiletine include: - Fine tremor of the hands - Dizziness and blurred vision - Gastrointestinal distress - Coordination difficulties Less common cardiovascular effects may include palpitations, chest pain, and angina-like pain. Hypotension, sinus bradycardia, and widening of the QRS complex have been noted with IV administration.
Q: Are there any precautions or contraindications for using Mexiletine?
A: Yes, Mexiletine is contraindicated in: - Patients with cardiogenic shock - Preexisting second- or third-degree heart block without a cardiac pacemaker Caution should be exercised when administering to patients with: - Sinus node dysfunction - Disturbances of intraventricular conduction Additionally, dose adjustments may be necessary when used with phenytoin or rifampin due to potential drug interactions.
Company Name | Contact | Product Details |
---|---|---|
Hefei TNJ Chemical Industry Co., Ltd. | 86 0551 65418679, 86 18949832763 | Purity: USP32, Package: 1KG $25USD |
Hubei Jusheng Technology Co., Ltd. | 18871490254 | Purity: 99%, Package: 5KG, 1KG |
Alchem PharmtechInc | 8485655694 | Purity: 97%, Package: 1g, 10g, 100g, 1kg |
TargetMol Chemicals Inc. | 1 781 999 5354 | Package: 100 mg, 500 mg |
This article was written by bob and published on 2024-08-04 20:38:45. Original article, reproduction is prohibited. The content is for entertainment purposes only and should not be taken as fact.
This article link: https://supply.beasts.cc/b2b/34b9b3970554b5a8.html