[R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride (CAS: 16777-42-7) Supplier Information

| Property | Information | |----------|-------------| | Product Name | [R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride | | Synonyms | Oxyfedrine hydrochloride, Ildamen, D-563 | | CAS Number | 16777-42-7 | | Molecular Formula | C19H24ClNO3 | | Molecular Weight | 349.85176 | | EINECS | 2408281 | | Melting Point | 192-194°C | | Form | Solid | | Color | White to off-white | | Purity | ≥97% (varies by supplier) |

[R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride, also known as Oxyfedrine hydrochloride, is a vasodilator and β-adrenoreceptor agonist. It is used as a coronary vasodilator and has been found to depress the tonicity of coronary vessels, improving myocardial circulation. The compound was originally developed by Ildamen Homburg in West Germany in 1966.

Frequently Asked Questions

**Q: What is the main therapeutic use of Oxyfedrine hydrochloride?** A: Oxyfedrine hydrochloride functions primarily as a coronary vasodilator. It helps to improve blood flow to the heart by dilating coronary blood vessels. Q: How is Oxyfedrine hydrochloride synthesized? A: The manufacturing process involves mixing m-methoxy acetophenone, paraformaldehyde, and 1-norephedrine with isopropanol HCl solution. The mixture is refluxed, cooled, and the resulting crystals are filtered and recrystallized from methanol. Q: What are the safety considerations for handling Oxyfedrine hydrochloride? A: While specific safety data is limited in the provided information, it's important to note that the LD50 in mice (intravenous) is 29 mg/kg. As with all chemical compounds, proper safety precautions should be taken when handling, and it should only be used for laboratory or prescribed medical purposes.

| Company Name | Contact Information | Product Details | |--------------|---------------------|------------------| | Alchem PharmtechInc | Tel: 8485655694 | Product Name: (3R)-3-(((1S)-1-Hydroxy-1-phenylpropan-2-yl)amino)-3-methoxy-1-phenylpropan-1-one hydrochloride
Purity: 97 %
Package: 1g, 10g, 100g, 1kg | | Career Henan Chemical Co. | Tel: 86 0371 86658258, 8613203830695 | Product Name: [R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride
Purity: ≥98%
Package: 1g | | TargetMol Chemicals Inc. | Tel: 1 781 999 5354 | Product Name: Oxyfedrine L-form HCl, Ildamen, Oxyfedrine L-form hydrochloride, D563, Modacor, D-563
Package: 100 mg, 500 mg | | Shaanxi Dideu Medichem Co., Ltd. | Tel: 86 029 89586680, 86 18192503167 | Product Name: [R-(R*,S*)]-3-[(2-hydroxy-1-methyl-2-phenylethyl)amino]-3'-methoxypropiophenone hydrochloride USP EP BP
Purity: 99.9%
Package: 25kgs Drum, 200kgs Drum | | Alfa Chemistry | Tel: 1 5166625404 | Product Name: Oxyfedrine hydrochloride
Purity: 97 % |