Sisomycin Sulfate (CAS 53179-09-2) Suppliers and Product Information

Sisomycin Sulfate is an aminoglycoside antibiotic used for its antibacterial properties. It binds to ribosomes and interferes with protein synthesis. The compound is produced through tank fermentation of Micromonospora inyoensis and undergoes several purification steps. It has similar antibacterial potency and effectiveness against aminoglycoside-inactivating enzymes as gentamicin.

Frequently Asked Questions about Sisomycin Sulfate

Q: What is the main use of Sisomycin Sulfate?

A: Sisomycin Sulfate is primarily used as an aminoglycoside antibiotic for its antibacterial properties. It can also be used as a reagent in structural and kinetics studies of self-assembling macrocyclic dimers and aminoglycoside variants.

Q: How does Sisomycin Sulfate work?

A: Sisomycin Sulfate works by binding to ribosomes and interfering with protein synthesis in bacteria, thus exhibiting its antibacterial effects.

Q: Is Sisomycin Sulfate approved for human use in the United States?

A: Although Sisomycin Sulfate has been approved for human use in the United States, it has not been marketed in the country.

Q: How does Sisomycin Sulfate compare to gentamicin?

A: Sisomycin Sulfate has similar antibacterial potency and effectiveness against aminoglycoside-inactivating enzymes as gentamicin. It also exhibits similar pharmacokinetics and pharmacological properties.

Q: What are the safety considerations for handling Sisomycin Sulfate?

A: Sisomycin Sulfate is considered poisonous by intravenous, intramuscular, intraperitoneal, and subcutaneous routes. When heated to decomposition, it emits very toxic fumes of SOx and NOx. Proper safety precautions should be taken when handling this compound.