Securinine (CAS 5610-40-2): Supplier Information and Product Details

Securinine is a GABA receptor antagonist extracted from the leaves and roots of Securinega suffruticosa Rehder. It has significant in vivo CNS activity and acts as a CNS stimulant. The compound is used in research as a GABAA receptor blocker.

Frequently Asked Questions about Securinine

Q: What is the main use of Securinine?

A: Securinine is primarily used as a GABA receptor antagonist in research. It has significant central nervous system (CNS) activity and is studied for its potential as a CNS stimulant.

Q: What is the source of Securinine?

A: Securinine is extracted from the leaves and roots of Securinega suffruticosa Rehder, a plant species. It is one of the most widely studied alkaloids from this plant.

Q: What are the physical properties of Securinine?

A: Securinine is a yellow solid with a molecular weight of 217.26 g/mol. It has a melting point of 140-142°C and is soluble in DMSO (≥25mg/mL). It is strongly laevorotatory, with an optical rotation [α]D between -980 to -1015° (c=1, MeOH).

Q: How should Securinine be stored?

A: Securinine should be stored sealed in a dry environment at a temperature between 2-8°C to maintain its stability.