Pefloxacin (CAS 70458-92-3) Suppliers and Product Information

Pefloxacin is a synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria. It inhibits DNA gyrase and is used to treat severe and life-threatening bacterial infections. Pefloxacin is available for oral and intravenous administration, with a plasma elimination half-life of 8.5-15 hours.

Frequently Asked Questions about Pefloxacin

Q: What are the main uses of Pefloxacin?

A: Pefloxacin is primarily used as an antibacterial agent to treat severe and life-threatening bacterial infections. It is effective against most gram-negative and gram-positive bacteria.

Q: What are the common side effects of Pefloxacin?

A: Common side effects of Pefloxacin include gastrointestinal tract disturbances, some central nervous system reactions, and skin eruptions (including photosensitive reactions). Long-term therapy may lead to rashes in some patients.

Q: How is Pefloxacin administered?

A: Pefloxacin is available for both oral and intravenous administration. A typical oral dose of 400 mg achieves a plasma concentration of about 5 mg/L within 1-1.5 hours.