Cefacetrile Sodium (CAS: 23239-41-0) Suppliers and Product Information

Cefacetrile sodium is a cephalosporin antibiotic with antibacterial properties. It was synthesized by Ciba-Geigy in 1970 and shows similar activity against gram-negative bacteria as cephalothin, with higher activity against β-lactamase-producing Escherichia coli. It has been used to treat sepsis, abdominal, and respiratory tract infections caused by Staphylococcus, Streptococcus, Escherichia coli, and Klebsiella pneumoniae.

Frequently Asked Questions about Cefacetrile Sodium

Q: What is the main use of Cefacetrile Sodium?

A: Cefacetrile Sodium is primarily used as a cephalosporin antibiotic with antibacterial properties. It is effective in treating various infections, including sepsis, abdominal, and respiratory tract infections caused by specific bacteria.

Q: How does Cefacetrile Sodium compare to other cephalosporins?

A: Cefacetrile Sodium shows similar activity against gram-negative bacteria as cephalothin but has higher activity against β-lactamase-producing Escherichia coli. However, it is gradually being replaced by newer and more active cephalosporins in clinical settings.

Q: What are the storage requirements for Cefacetrile Sodium?

A: Cefacetrile Sodium should be stored in a -20°C freezer under an inert atmosphere. It is hygroscopic, meaning it readily absorbs moisture from the air, which can affect its stability.

Q: Is Cefacetrile Sodium still widely used in clinical practice?

A: While Cefacetrile Sodium has been used effectively in the past, it is gradually being replaced by newer and more active cephalosporins in clinical practice. However, it may still be used in specific cases or regions where newer alternatives are not available or appropriate.