Gatifloxacin Mesylate (CAS 316819-28-0) Suppliers and Product Information

Product Name	CAS Number	Molecular Formula	Molecular Weight
Gatifloxacin Mesylate	316819-28-0	C19H22FN3O4·CH4O3S	471.503

Gatifloxacin mesylate is a fourth-generation fluoroquinolone antibiotic with broad-spectrum antibacterial activity. It functions as a bacterial DNA gyrase inhibitor and is used to treat various bacterial infections, including tuberculosis and pneumonia. The compound inhibits bacterial type II topoisomerase, with IC50 values of 13.8 μg/ml for S. aureus topoisomerase IV and 0.109 μg/ml for E. coli DNA rotamase.

Key properties and uses:

- Soluble in DMSO - Stored at -20°C - Used to treat bacterial conjunctivitis in vivo - Injectable form used for acute urinary tract infections, with efficacy comparable to levofloxacin hydrochloride injection - Inhibits bacterial enzymes DNA gyrase and topoisomerase IV

Frequently Asked Questions

Q: What is the primary use of Gatifloxacin Mesylate?

A: Gatifloxacin Mesylate is primarily used as a broad-spectrum antibiotic to treat various bacterial infections, including tuberculosis, pneumonia, and bacterial conjunctivitis. It is also effective in treating acute urinary tract infections.

Q: How does Gatifloxacin Mesylate work?

A: Gatifloxacin Mesylate works by inhibiting bacterial DNA gyrase and topoisomerase IV enzymes. This action disrupts bacterial DNA replication and ultimately leads to cell death, effectively combating bacterial infections.

Q: What is the purity range of commercially available Gatifloxacin Mesylate?

A: Based on the supplier information provided, commercially available Gatifloxacin Mesylate typically has a purity range of 98% to 99.9% (HPLC).

Company Name	Contact	Product Details
Shandong Perfect Biotechnology Co Ltd	86 53169958659, 8618596095638	Gatifloxacin mesylate, Purity: 98% (HPLC), Package: 1g
Henan Suikang Pharmaceutical Co Ltd	86 18239973690	GATIFLOXACIN MESYLATE, Purity: 99.0%, Package: 25kg
Career Henan Chemical Co	86 0371 86658258, 8613203830695	GATIFLOXACIN MESYLATE, Purity: 99%, Package: 3KG
Chongqing Chemdad Co, Ltd	86 023 6139 8061, 86 13650506873	GATIFLOXACIN MESYLATE, Purity: 98%, Package: 1kg, 2kg, 5kg, 10kg, 25kg
Shaanxi Dideu Medichem Co, Ltd	18192627656	Gatifloxacin mesylate, Purity: 99%, Package: 1KG, 25KG, 200KG