Property | Value |
---|---|
Chemical Name | Gallamine Triethiodide |
CAS Number | 65-29-2 |
Molecular Formula | C₃₀H₆₀I₃N₃O₃ |
Molecular Weight | 891.53 |
Appearance | White powder/crystals |
Melting Point | 235°C (dec.) |
Solubility | 100-160 mg/mL in H₂O |
Gallamine Triethiodide, also known as Flaxedil, is a neuromuscular blocking agent used as a muscle relaxant during anesthesia. It acts as an antagonist at muscarinic receptors, particularly M2 receptors. The compound is used in research for measuring spinal trigeminal nucleus recordings and reducing eye movement during retinal surgery in rats.
Q: What is the primary use of Gallamine Triethiodide?
A: Gallamine Triethiodide is primarily used as a neuromuscular blocking agent and muscle relaxant during anesthesia. It also has applications in research, particularly for neurological studies.
Q: Is Gallamine Triethiodide safe to use?
A: Gallamine Triethiodide should be used with caution. It is contraindicated in patients with myasthenia gravis, and its action is cumulative. The antidote for Gallamine Triethiodide is neostigmine. Always follow proper medical guidelines and dosages when using this compound.
Q: How does Gallamine Triethiodide work?
A: Gallamine Triethiodide works by blocking neuromuscular transmission in a manner similar to d-tubocurarine. It is a non-depolarizing blocking agent with strong vagolytic effects and muscarinic antagonistic properties, binding with greater affinity to M2 receptors than M1 receptors.
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