Hematoporphyrin (CAS 14459-29-1) Suppliers and Product Information

Hematoporphyrin is an iron-free derivative of heme with four methyl groups, two hydroxyethyl groups, and two propionic acid groups attached to the pyrrole rings. It is used as a photosensitizer in photodynamic therapy and has been used as an antidepressant and antipsychotic since the 1920s. Hematoporphyrin is also used as a substrate for affinity chromatography of heme-binding proteins.

Frequently Asked Questions about Hematoporphyrin

Q: What is the main use of Hematoporphyrin?

A: Hematoporphyrin is primarily used as a photosensitizer in photodynamic therapy. It has also been used as an antidepressant and antipsychotic agent.

Q: How should Hematoporphyrin be stored?

A: Hematoporphyrin should be stored sealed in a dry environment at 2-8°C. It is light-sensitive, so it should be protected from light.

Q: What is the significance of Hematoporphyrin in cancer research?

A: Hematoporphyrin is reported to be preferentially absorbed by cancerous tissues, making them fluoresce under UV light. This property makes it useful in cancer detection and treatment.

Q: How is Hematoporphyrin purified?

A: Hematoporphyrin can be purified by dissolving it in ethanol and adding water or ether to produce deep red crystals. It can also be recrystallized from methanol.