TOCAINIDE (CAS 41708-72-9) Suppliers and Product Information

Tocainide is an antiarrhythmic agent used for suppressing symptoms of ventricular arrhythmia and tachycardia, and for premature cardiac contractions. It is a monocarboxylic acid amide in which 2,6-dimethylphenylaniline and isobutyric acid have combined to form the amide bond. Tocainide is used as a local anesthetic and was introduced in 1981 for the treatment of ventricular dysrhythmias.

Frequently Asked Questions about Tocainide

Q: What is the main use of Tocainide?

A: Tocainide is primarily used as an antiarrhythmic agent for the treatment of symptomatic ventricular arrhythmias that are refractory to more conventional therapy.

Q: What are the common side effects of Tocainide?

A: Common side effects include light-headedness, dizziness, nausea, paresthesias, numbness, and tremor. These effects are generally mild, transient, and dose-related. However, serious immune-based side effects such as pulmonary fibrosis and blood dyscrasias have been reported.

Q: How is Tocainide administered?

A: Tocainide is an orally effective antiarrhythmic agent, which distinguishes it from lidocaine, to which it is structurally similar.

Q: Are there any precautions or contraindications for Tocainide use?

A: Tocainide should not be used in patients hypersensitive to tocainide or local anesthetics of the amide type. It is also contraindicated in patients with second- or third-degree heart block in the absence of an artificial pacemaker.