Property | Value |
---|---|
Chemical Name | Nefopam Hydrochloride |
CAS Number | 23327-57-3 |
Molecular Formula | C17H20ClNO |
Molecular Weight | 289.8 |
Synonyms | 5-Methyl-1-phenyl-3,4,5,6-tetrahydro-1H-benzo[f][1,4]oxazocine Hydrochloride |
Appearance | White to off-white solid |
Melting Point | 238-242°C |
Solubility | Soluble in water (5mg/mL, clear) |
Storage | 2-8°C |
Nefopam hydrochloride is a centrally acting ***gesic drug of the benzoxazocine chemical class. It is used for moderate pain relief and has a non-opioid mechanism of action. The compound is extensively metabolized in the liver and primarily excreted in urine.
Q: What is the main use of Nefopam hydrochloride?
A: Nefopam hydrochloride is primarily used as an ***gesic for moderate pain. It acts as a centrally acting muscle relaxant and has potential antidepressant properties.
Q: How does Nefopam hydrochloride work?
A: While its exact mechanism of action is not fully understood, Nefopam hydrochloride is believed to act as a dopamine, serotonin, and norepinephrine reuptake inhibitor. It is non-opioid but can potentiate the effects of *** and other opioids.
Q: Are there any significant drug interactions with Nefopam hydrochloride?
A: Yes, Nefopam hydrochloride may have potentially hazardous interactions with other drugs. It should be avoided with MAOIs (Monoamine Oxidase Inhibitors), and there may be an increased risk of side effects when used with tricyclic antidepressants.
Q: How is Nefopam hydrochloride metabolized and eliminated from the body?
A: Nefopam hydrochloride is extensively metabolized in the liver, producing active metabolites. It is mainly excreted in the urine, with about 8% of a dose being excreted via feces.
Company Name | Contact | Product Details |
---|---|---|
Xiamen Wonderful Bio Technology Co., Ltd. | Tel: 8613043004613 | Purity: 99.8%, Package: 1KG, Price: $120.00 USD |
Liaoning Pharmaceutical Innovation Co., Ltd. | Tel: 8616588669988 | Purity: 99%, Package: 1kg, Price: $10 USD (1000kg: $5 USD) |
Henan Tianfu Chemical Co., Ltd. | Tel: 86 0371 55170693, 86 19937530512 | Purity: 99%, Package: 25KG, 5KG, 1KG |
Career Henan Chemical Co. | Tel: 86 0371 86658258, 8613203830695 | Purity: 98%, Package: 1KG, Price: $1 USD |
Hubei Jusheng Technology Co., Ltd. | Tel: 18871490254 | Purity: 99%, Package: 5KG, 1KG |
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