Property | Value |
---|---|
Product Name | Metoprolol |
CAS Number | 37350-58-6 |
Molecular Formula | C15H25NO3 |
Molecular Weight | 267.36 |
EINECS | 253-483-7 |
Category | Cardiovascular |
Metoprolol is a β-adrenergic blocking agent used for treating hypertension, angina, and other cardiovascular conditions. It acts as an antihypertensive and antianginal agent. Metoprolol is also used for secondary prophylaxis after heart attacks and for preventing migraine attacks.
Chemical Properties: - Boiling point: 410.55°C (rough estimate) - Density: 1.0281 (rough estimate) - Refractive index: 1.5000 (estimate)
Metoprolol is readily absorbed after oral administration and undergoes significant first-pass metabolism in the liver. It has a plasma half-life ranging from 0.5 to 2.5 hours, with only 3-10% of the administered dose recovered as unchanged drug.
Q: What is the main use of Metoprolol?
A: Metoprolol is primarily used to treat moderate hypertension, serious conditions of myocardial infarction, angina, tachycardia, and for secondary prophylaxis after a heart attack. It's also used to prevent attacks of migraine and in some ophthalmic preparations.
Q: How does Metoprolol work?
A: Metoprolol is a cardioselective β1-adrenergic receptor blocker. In therapeutic doses, it blocks β1-adrenoreceptors with insignificant effects on β2-adrenoreceptors, making it different from non-selective beta-blockers like propranolol.
Q: What are the key chemical properties of Metoprolol?
A: Metoprolol has a molecular formula of C15H25NO3 and a molecular weight of 267.36. It's a propanolamine compound that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Q: How is Metoprolol metabolized in the body?
A: Metoprolol is rapidly absorbed and undergoes significant first-pass metabolism in the liver. Only 3-10% of an administered dose is recovered as unchanged drug. The metabolites are primarily eliminated through renal excretion, with small amounts present in feces.
Company Name | Contact | Product Details |
---|---|---|
Wuhan Quanjinci New Material Co Ltd | Tel: 86 15271838296 | Purity: ≥99%, Package: 1kg, Price: 12 USD |
Career Henan Chemical Co | Tel: 86 0371 86658258, 86 13203830695 | Purity: 99%, Package: 1KG, Price: 7 USD |
Hefei TNJ Chemical Industry Co Ltd | Tel: 0551 65418671 | Not specified |
Dorne Chemical Technology Co., LTD | Tel: 86 13583358881, 86 18560316533 | Purity: ≥99% |
Hebei Lingding Biotechnology Co., Ltd | Tel: 86 18031140164, 86 19933155420 | Purity: 99%, Package: 1KG, Price: 30 USD |
This article was written by bob and published on 2024-07-23 06:10:04. Original article, reproduction is prohibited. The content is for entertainment purposes only and should not be taken as fact.
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