Ethyl 2-oxo-4-phenylbutyrate (CAS 64920-29-2) Suppliers and Product Information

Ethyl 2-oxo-4-phenylbutyrate is an aliphatic α-ketoester used in the synthesis of ethyl (R)-2-hydroxy-4-phenylbutyrate, an important chiral precursor for angiotensin-converting enzyme (ACE) inhibitors. It is slightly soluble in chloroform and ethyl acetate.

Frequently Asked Questions

Q: What are the main uses of Ethyl 2-oxo-4-phenylbutyrate?

A: Ethyl 2-oxo-4-phenylbutyrate is primarily used as a precursor in the synthesis of ethyl (R)-2-hydroxy-4-phenylbutyrate, which is an important chiral intermediate for producing angiotensin-converting enzyme (ACE) inhibitors.

Q: What are the storage conditions for Ethyl 2-oxo-4-phenylbutyrate?

A: Ethyl 2-oxo-4-phenylbutyrate should be stored sealed in a dry environment at room temperature.

Q: What are some common synthesis methods for Ethyl 2-oxo-4-phenylbutyrate?

A: One method involves reacting a diester with potassium tert-butoxide in toluene, followed by purification through flash chromatography.