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Lorcaserin Hydrochloride (CAS 846589-98-8): Properties, Uses, and Supplier Information

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  • 2024-07-14 21:14:01
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PropertyInformation
Product NameLorcaserin hydrochloride
CAS Number846589-98-8
Molecular FormulaC11H15Cl2N
Molecular Weight232.15 g/mol
SynonymsAPD356, Belviq, (1R)-8-Chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine hydrochloride

Lorcaserin hydrochloride is a selective serotonin 5-HT2C receptor agonist approved by the FDA in 2012 as an anti-obesity drug. It is used for chronic weight management in *** patients who are overweight or obese and have at least one comorbid weight-related condition. The compound is soluble in DMSO (10 mM) and comes in powder form.

Frequently Asked Questions about Lorcaserin Hydrochloride

2Lorcaserin Hydrochloride (CAS 846589-98-8): Properties, Uses, and Supplier Information

Q: What is the primary use of Lorcaserin hydrochloride?

A: Lorcaserin hydrochloride is primarily used as an anti-obesity drug for chronic weight management in overweight or obese ***s with at least one weight-related comorbid condition.

Q: How does Lorcaserin hydrochloride work?

A: Lorcaserin hydrochloride works as a selective serotonin 5-HT2C receptor agonist. It primarily affects the hypothalamus, regulating appetite and feeding behavior.

Q: What are the common side effects of Lorcaserin hydrochloride?

A: Common side effects include nausea, headache, dizziness, nasopharyngitis, and fatigue. It may also increase the risk of symptomatic hypoglycemia in patients with type 2 diabetes on oral agents.

Q: Are there any precautions or drug interactions to be aware of when using Lorcaserin hydrochloride?

A: Yes, Lorcaserin hydrochloride should not be used with other serotonergic drugs due to the potential risk of serotonin syndrome. It is also contraindicated during pregnancy and in individuals with creatinine clearance <30 mL/minute.

SupplierProduct NamePrice
Cayman ChemicalLorcaserin (hydrochloride) (APD356)$32.00
Sigma-AldrichLorcaserin hydrochloride ≥98% (HPLC)Not specified
FunakoshiLorcaserin (hydrochloride)Not specified