ERYTHROMYCIN LACTOBIONATE (200 MG) CAS 3847-29-8: Suppliers and Product Information

Erythromycin lactobionate is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit. It is effective against various bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus. The lactobionate salt form is typically used for intraperitoneal or intravenous injections due to its water solubility.

This compound is used as an antibiotic to reduce the prevalence of drug-resistant bacteria and maintain the efficacy of other antibacterial drugs. It is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications.

Frequently Asked Questions

Q: What is the primary use of Erythromycin Lactobionate?

A: Erythromycin Lactobionate is primarily used as an antibiotic for intravenous administration to achieve high plasma levels in the treatment of serious bacterial infections.

Q: How is Erythromycin Lactobionate manufactured?

A: Erythromycin Lactobionate is manufactured by reacting erythromycin free base with lactobiono-delta-lactone. The resulting solution is evaporated, dissolved in water, frozen, and dried in vacuum by lyophilization to produce a white amorphous powder.

Q: What are the storage requirements for Erythromycin Lactobionate?

A: Erythromycin Lactobionate should be stored in a refrigerator to maintain its stability and efficacy.

Q: Is Erythromycin Lactobionate available under any brand names?

A: Yes, Erythromycin Lactobionate is available under brand names such as Erythrocin (Abbott) and Erythrocin (Hospira).