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PF-04971729 (Ertugliflozin) CAS 1210344-57-2 Suppliers and Product Information

bob
API
2024-07-15 15:39:35
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Property	Value
Product Name	PF-04971729 (Ertugliflozin)
CAS Number	1210344-57-2
Molecular Formula	C22H25ClO7
Molecular Weight	436.88
Melting Point	65 - 66°C
Boiling Point	630.5±55.0 °C (Predicted)
Density	1.455
Storage Temperature	Sealed in dry, Store in freezer, under -20°C
Solubility	DMSO: Slightly, Methanol: Slightly
pKa	12.95±0.70 (Predicted)
Form	Solid
Color	White to Off-White

PF-04971729, also known as Ertugliflozin, is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2). It has an IC50 of 0.927 nM for the human enzyme and is selective for SGLT2 over SGLT1. Ertugliflozin is used in the treatment of type 2 diabetes and is currently in phase 2 clinical trials.

Frequently Asked Questions

2PF-04971729 (Ertugliflozin) CAS 1210344-57-2 Suppliers and Product Information

Q: What is the mechanism of action of PF-04971729 (Ertugliflozin)?

A: PF-04971729 (Ertugliflozin) is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It works by blocking the SGLT2 protein in the kidneys, which is responsible for reabsorbing glucose from the urine. By inhibiting SGLT2, Ertugliflozin increases glucose excretion through urine, thereby lowering blood glucose levels in patients with type 2 diabetes.

Q: What is the typical purity of PF-04971729 available from suppliers?

A: Based on the supplier information provided, the typical purity of PF-04971729 (Ertugliflozin) ranges from 98% to 99%.

Q: How should PF-04971729 be stored?

A: PF-04971729 should be stored sealed in a dry environment, preferably in a freezer at temperatures below -20°C.

Company Name	Contact	Product Details
Henan Tianfu Chemical Co., Ltd.	Tel: 86 0371 55170693, 86 19937530512	Purity: 99%, Package: 25KG/5KG/1KG
Nanjing ChemLin Chemical Industry Co., Ltd.	Tel: 025 83697070	Purity: 98%, Package: g/Kg, White powder
ATK CHEMICAL COMPANY LIMITED	Tel: 21 51877795	Purity: 98%, Package: 10MG/50MG/100MG/1G/5G/10G/100G
Anqing Chico Pharmaceutical Co., Ltd.	Tel: 15380796838	Purity: 99%, Package: 10g/100g/1kg/25kg or More
Hubei xin bonus chemical co., LTD	Tel: 86 13657291602	Purity: ≥99%, Supply Ability: 1 ton

This article was written by bob and published on 2024-07-15 15:39:35. Original article, reproduction is prohibited. The content is for entertainment purposes only and should not be taken as fact.
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