2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine (CAS 3605-01-4) Suppliers and Product Information

2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine, also known as Piribedil, is an antiparkinsonian agent that acts as a dopamine agonist. It also displays α2-adrenergic antagonist properties. Piribedil has been shown to counteract age-related memory impairment by improving memory and attention, as well as increasing the velocity of psychomotor reactions and lability of nervous processes.

Frequently Asked Questions

Q: What is the main use of 2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine?

A: The compound, also known as Piribedil, is primarily used as an antiparkinsonian agent and vasodilator. It acts as a dopamine agonist and has α2-adrenergic antagonist properties.

Q: What are the potential side effects of Piribedil?

A: As a vasodilator and antiparkinsonian medication, Piribedil may cause side effects such as dizziness, nausea, and changes in blood pressure. However, specific side effects should be discussed with a healthcare professional.

Q: How is 2-[4-(1,3-Benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine synthesized?

A: The compound is synthesized by reacting 1-(3,4-methylenedioxybenzyl)piperazine with 2-chloropyrimidine in the presence of anhydrous potassium carbonate and xylene. The mixture is heated, extracted, and purified to obtain the final product.