Oxprenolol Hydrochloride (CAS 6452-73-9) Suppliers and Product Information

Oxprenolol hydrochloride is a non-selective β-adrenergic receptor antagonist used in the treatment of hypertension, angina pectoris, arrhythmias, and anxiety. It is orally bioavailable and binds to both β1 and β2 adrenergic receptors. The compound is extensively metabolized in the liver, primarily through direct O-glucuronidation, and is excreted mainly in the urine as inactive metabolites.

Frequently Asked Questions about Oxprenolol Hydrochloride

Q: What are the main uses of Oxprenolol Hydrochloride?

A: Oxprenolol Hydrochloride is primarily used as an antihypertensive, antianginal, and antiarrhythmic agent. It is also used to treat anxiety.

Q: How does Oxprenolol Hydrochloride work?

A: Oxprenolol Hydrochloride is a non-selective β-adrenergic receptor antagonist, which means it blocks both β1 and β2 receptors. This action helps to reduce heart rate, cardiac output, and blood pressure.

Q: Are there any significant drug interactions with Oxprenolol Hydrochloride?

A: Yes, Oxprenolol Hydrochloride can interact with various medications, including anaesthetics, NSAIDs, anti-arrhythmics, antidepressants, other antihypertensives, antimalarials, antipsychotics, and certain sympathomimetics. It's important to consult with a healthcare professional about potential drug interactions.

Q: How is Oxprenolol Hydrochloride metabolized and eliminated from the body?

A: Oxprenolol Hydrochloride is extensively metabolized in the liver, primarily through direct O-glucuronidation. It is excreted mainly in the urine, almost exclusively in the form of inactive metabolites.