Ophthazin (CAS 484-23-1) Suppliers and Product Information

Ophthazin, also known as dihydralazine, is an antihypertensive agent of the hydrazine class. It is used during pregnancies in dialysis patients with familial Mediterranean fever and cystinosis under hemodialysis. The compound belongs to the categories of aromatics, heterocycles, intermediates, fine chemicals, and pharmaceuticals.

**Safety Information:** HS Code: 2933998090 Toxicity: LD50 (i.p. in rats) 1084 mmol/kg

**Manufacturing Process:** The synthesis involves reacting hydrazine hydrate with phthalic acid dinitrile in dioxane and acetic acid, followed by heating, crystallization, and purification steps.

**Therapeutic Function:** Antihypertensive

**Safety Profile:** Poison by intravenous route. An experimental teratogen. When heated to decomposition, it emits toxic fumes of NOx.

Frequently Asked Questions about Ophthazin

**Q: What is the main use of Ophthazin?**

A: Ophthazin, also known as dihydralazine, is primarily used as an antihypertensive agent. It is particularly useful for treating hypertension in pregnant women undergoing dialysis, especially those with conditions like familial Mediterranean fever and cystinosis.

**Q: What class of drugs does Ophthazin belong to?**

A: Ophthazin belongs to the hydrazine class of antihypertensive agents.

**Q: Are there any safety concerns when using Ophthazin?**

A: Yes, there are several safety concerns to be aware of: 1. It is considered a poison when administered intravenously. 2. It has been identified as an experimental teratogen, which means it may cause birth defects. 3. When heated to decomposition, it releases toxic fumes of nitrogen oxides (NOx). 4. As with any medication, it should only be used under the supervision of a healthcare professional.

**Q: What is the appearance of Ophthazin?**

A: Ophthazin is predicted to form orange crystals when crystallized from water.