Suplatast Tosilate (CAS 94055-76-2) Suppliers and Product Information

Suplatast tosilate is an antiallergic agent that inhibits IL-4 and IL-5 production in T cells. It is used for the treatment of bronchial asthma, atopic dermatitis, and allergic rhinitis. The compound acts as an immunoregulator by suppressing IgE production, eosinophil infiltration, and histamine release. It exhibits antiasthmatic, anti-inflammatory, and antifibrotic activity in vivo and is orally active.

Frequently Asked Questions about Suplatast Tosilate

Q: What is the primary use of Suplatast tosilate?

A: Suplatast tosilate is primarily used as an antiallergic drug for the treatment of bronchial asthma, atopic dermatitis, and allergic rhinitis. It works by inhibiting IgE synthesis and suppressing the production of certain interleukins (IL-4 and IL-5) by T cells.

Q: How does Suplatast tosilate work?

A: Suplatast tosilate acts as a Th2 cytokine inhibitor. It attenuates the production of IL-2, IL-5, and IL-13 without affecting IFN-γ production. This mechanism helps in suppressing IgE production, eosinophil infiltration, and histamine release, which are key factors in allergic responses.

Q: What is the recommended storage condition for Suplatast tosilate?

A: Suplatast tosilate should be stored at room temperature in an inert atmosphere. The compound is stable for 1 year from the date of purchase when supplied. Solutions in DMSO or distilled water can be stored at -20°C for up to 3 months.

Q: Is Suplatast tosilate available for research purposes?

A: Yes, Suplatast tosilate is available for research purposes from various chemical suppliers. It's important to note that purity levels and packaging sizes may vary among suppliers.