Escitalopram Oxalate (CAS 219861-08-2) Suppliers and Product Information

Escitalopram oxalate is the S-enantiomer of citalopram, a selective serotonin reuptake inhibitor (SSRI) used for the treatment of depression and anxiety disorders. It is more potent and selective than the racemic citalopram, exhibiting higher efficacy in inhibiting serotonin reuptake in vivo. Escitalopram has linear pharmacokinetics with a long half-life of 27-32 hours and is extensively metabolized in the liver via cytochrome P450 enzymes.

Frequently Asked Questions about Escitalopram Oxalate

Q: What is the main use of Escitalopram oxalate?

A: Escitalopram oxalate is primarily used for the treatment of depression and panic disorder. It is a selective serotonin reuptake inhibitor (SSRI) that helps increase serotonin levels in the brain.

Q: How does Escitalopram oxalate compare to citalopram?

A: Escitalopram is the S-enantiomer of citalopram and is considered to be twice as effective as the racemic citalopram. It also exhibits higher selectivity for the human serotonin transporter compared to other available SSRIs.

Q: What are the common side effects of Escitalopram?

A: The most common side effects of Escitalopram include nausea, dry mouth, trouble sleeping, constipation, tiredness, drowsiness, dizziness, and increased sweating.

Q: How is Escitalopram metabolized in the body?

A: Escitalopram is extensively metabolized in the liver via cytochrome P450 enzymes to S-desmethyl and S-didesmethyl citalopram. However, it has been shown to be a weak or negligible inhibitor of CYP450 drug-metabolizing enzymes in vitro.