Ansamitocin P-3 (CAS 66584-72-3) Suppliers and Product Information

Ansamitocin P-3 is a fungal metabolite with antimitotic and antineoplastic activity. It binds to tubulin and inhibits vinblastine-induced spiral formation. This compound is primarily used for research purposes in cell signaling, neuroscience, and cytoskeleton studies, particularly as a microtubule inhibitor.

Frequently Asked Questions

Q: What is the primary use of Ansamitocin P-3?

A: Ansamitocin P-3 is primarily used as an antitumor agent in research. It works by depolymerizing microtubules in both interphase and mitosis, disrupting chromosome segregation.

Q: How should Ansamitocin P-3 be stored?

A: Ansamitocin P-3 should be stored in a dark place, under an inert atmosphere, and kept in a freezer at temperatures below -20°C.

Q: What is the solubility of Ansamitocin P-3?

A: Ansamitocin P-3 is soluble in DMSO (100 mg/mL, 157.45 mM) and ethanol (55 mg/mL, 86.60 mM). It is insoluble in water.