1,5-dideoxy-1,5-[[2-[4-(ethoxycarbonyl)phenoxy]ethyl]imino]-D-glucitol (CAS: 80879-63-6) Supplier Information

Emiglitate (BAY O 1248) is a deoxynojirimycin ***ogue with at least five-fold higher inhibitory potency than acarbose. It shows a long-lasting inhibitory effect and remains active up to 17 hours after a single oral administration due to its pharmacokinetic behavior and the formation of an active metabolite. Unlike acarbose, which is poorly absorbed, emiglitate and miglitol are structurally related to monosaccharides and are absorbed in the jejunum.

Frequently Asked Questions

Q: What is the primary use of 1,5-dideoxy-1,5-[[2-[4-(ethoxycarbonyl)phenoxy]ethyl]imino]-D-glucitol?

A: This compound, also known as emiglitate or BAY O 1248, is primarily used as a potent inhibitor in research related to carbohydrate metabolism and diabetes treatment. It shows higher inhibitory potency than acarbose and has a long-lasting effect.

Q: How does emiglitate differ from acarbose in terms of absorption?

A: Emiglitate is absorbed in the jejunum due to its structural similarity to monosaccharides, while acarbose is poorly absorbed. This difference in absorption contributes to emiglitate's longer-lasting inhibitory effect.

Q: What are the recommended storage conditions for this compound?

A: The recommended storage temperature for 1,5-dideoxy-1,5-[[2-[4-(ethoxycarbonyl)phenoxy]ethyl]imino]-D-glucitol is -20°C. It should be kept in a cool, dry place and protected from light and moisture.