Property | Value |
---|---|
Chemical Name | Cefmetazole sodium |
CAS Number | 56796-39-5 |
Molecular Formula | C15H16N7NaO5S3 |
Molecular Weight | 493.516 g/mol |
Appearance | White to off-white powder |
Solubility | Soluble in water (92 mg/mL) |
Storage | 2-8°C, inert atmosphere |
Melting Point | 130°C (dec.) |
Cefmetazole sodium is a semisynthetic cephamycin antibiotic with broad-spectrum activity against gram-positive and gram-negative bacteria. It is used clinically for treating various bacterial infections, including pulmonary infections. The compound is hygroscopic and sensitive to moisture.
Q: What is the mechanism of action of cefmetazole sodium?
A: Cefmetazole sodium interferes with bacterial cell wall synthesis. As a cephalosporin antibiotic, it inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, leading to cell lysis.
Q: What are the main clinical uses of cefmetazole sodium?
A: Cefmetazole sodium is used to treat various bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and gynecological infections. It is particularly effective against many Enterobacteriaceae and some anaerobic bacteria.
Q: How does cefmetazole sodium compare to other cephalosporins?
A: Cefmetazole is a third-generation cephalosporin of the cephamycin group. It has higher potency against Enterobacteriaceae compared to some other cephalosporins, but lower activity against Bacteroides species. Its 7α-methoxyl group provides resistance to many β-lactamases.
Company Name | Contact | Product Details |
---|---|---|
Shaanxi TNJONE Pharmaceutical Co., Ltd. | Tel: 8618740459177 | Purity: 99%, Package: 1kg |
Career Henan Chemical Co. | Tel: 86 0371 86658258, 8613203830695 | Purity: 99%, Package: 1KG, Price: 100USD |
Hubei Jusheng Technology Co Ltd | Tel: 18871490254 | Purity: 99%, Package: 5KG/1KG |
Hebei Guanlang Biotechnology Co., Ltd. | Tel: 86 19930503282 | Purity: 99%, Package: 1PCS, Price: 1USD |
Hubei xin bonus chemical co., LTD | Tel: 86 13657291602 | Purity: 99%, Package: 5KG/1KG |
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