Antazoline (CAS 91-75-8) Suppliers and Product Information

Antazoline is an ethylenediamine derivative with histamine H1 antagonistic and sedative properties. It is used as an antihistamine, particularly for local application to the eye in allergic conjunctivitis. The compound acts by antagonizing histamine H1 receptors.

Frequently Asked Questions about Antazoline

Q: What is the primary use of Antazoline?

A: Antazoline is primarily used as an antihistamine, particularly for local application to the eye in treating allergic conjunctivitis.

Q: What are the safety considerations when handling Antazoline?

A: Antazoline can be poisonous if ingested, or administered subcutaneously or intraperitoneally. It is also an eye irritant. When heated to decomposition, it emits toxic fumes of NOx. Proper safety precautions should be taken when handling this compound.

Q: How is Antazoline synthesized?

A: Antazoline is typically synthesized by reacting 2-chloromethylimidazoline hydrochloride with N-benzylaniline in alcohol under specific temperature conditions. The process involves heating, distillation, and extraction steps to obtain the final product.