Pilsicainide Hydrochloride (CAS 88069-49-2) Suppliers and Product Information

Pilsicainide hydrochloride is a class Ic antiarrhythmic agent and a pure sodium channel blocker. It is used for the treatment of premature ventricular contraction and has no anticholinergic or CNS activity. The compound is effective in inducing Brugada syndrome in animal models and is used to study electrophysiological effects in various cardiac preparations.

Frequently Asked Questions about Pilsicainide Hydrochloride

Q: What is the main use of Pilsicainide hydrochloride?

A: Pilsicainide hydrochloride is primarily used as an antiarrhythmic agent for the treatment of premature ventricular contraction. It is classified as a class Ic antiarrhythmic drug and functions as a pure sodium channel blocker.

Q: How does Pilsicainide hydrochloride work?

A: Pilsicainide hydrochloride works by selectively blocking sodium channels in cardiac tissue. It is an open channel blocker of Na channels and is capable of selectively blocking late currents in mutant Na channels that show abnormal burst openings.

Q: Are there any specific storage requirements for Pilsicainide hydrochloride?

A: Pilsicainide hydrochloride should be stored at room temperature or frozen (below 0°C). It should be kept away from heat.

Q: What is the typical purity of commercially available Pilsicainide hydrochloride?

A: The purity of commercially available Pilsicainide hydrochloride typically ranges from ≥95% to 99.9%, depending on the supplier and intended use.