Hexamethonium Bromide (CAS 55-97-0) Suppliers and Product Information

Hexamethonium bromide is a peripherally acting nondepolarizing neuromuscular blocking agent that acts as an antagonist of nicotinic acetylcholine receptors (nAChRs). It is used as an autonomic ganglia blocking agent in research to study effects on various physiological processes.

Frequently Asked Questions

Q: What are the main uses of hexamethonium bromide?

A: Hexamethonium bromide is primarily used in research as a nicotinic acetylcholine receptor antagonist. It has been used to study effects on whisker movement in rats, antigen-induced arthritis progression in mice, and autonomic cardiovascular responses. Historically, it was also used in the treatment of hypertension.

Q: How does hexamethonium bromide work?

A: Hexamethonium bromide acts as an antagonist at nicotinic acetylcholine receptors, preferentially blocking receptors at autonomic ganglia. It decreases acetylcholine release and can reduce mean arterial pressure in animal models.

Q: What are the storage requirements for hexamethonium bromide?

A: Hexamethonium bromide should be stored at room temperature in an inert atmosphere to maintain its stability.