Property | Value |
---|---|
Product Name | Meclofenamate Sodium |
CAS Number | 6385-02-0 |
Molecular Formula | C14H10Cl2NO2·Na |
Molecular Weight | 318.13 |
Melting Point | 287-291°C |
Appearance | White to Off-White solid |
Solubility | Soluble in water (50mg/ml), DMF, DMSO, ethanol |
Meclofenamate Sodium is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of mild to moderate pain, rheumatoid arthritis, osteoarthritis, and primary dysmenorrhea. It acts as a time-dependent, non-specific competitive inhibitor of COX-1 and COX-2 enzymes.
The compound is rapidly absorbed following oral administration, reaching peak plasma levels within 2 hours. It is highly protein-bound (99%) and has a plasma half-life of 2 to 4 hours. Metabolism involves oxidation, aromatic hydroxylation, monodehalogenation, and conjugation, with approximately 75% of the administered dose excreted in urine.
Q: What are the main uses of Meclofenamate Sodium?
A: Meclofenamate Sodium is primarily used for the relief of mild to moderate pain, treatment of acute and chronic rheumatoid arthritis and osteoarthritis, management of primary dysmenorrhea, and treatment of idiopathic heavy menstrual blood loss.
Q: What are the potential side effects of Meclofenamate Sodium?
A: The most significant side effects of Meclofenamate Sodium are gastrointestinal, including diarrhea. As with other NSAIDs, it may also cause stomach upset, bleeding, and ulcers.
Q: How should Meclofenamate Sodium be stored?
A: Meclofenamate Sodium should be kept in a dark place at room temperature. It is hygroscopic, so it should be protected from moisture.
Company Name | Contact | Product Details |
---|---|---|
CONIER CHEM AND PHARMA LIMITED | Tel: 8618523575427 | Purity: ≥99%, Package: 1kg |
TargetMol Chemicals Inc. | Tel: 1-781-999-5354 | Purity: 99.08%, Package: 1 mL (10mM in DMSO), 25mg, 50mg, 100mg, 200mg |
Dideu Industries Group Limited | Tel: 86-29-89586680, 86-15129568250 | Purity: 99.9%, Package: 1g |
AFINE CHEMICALS LIMITED | Tel: 86-0571-85134551 | Purity: ≥98%, Package: Standard or custom |
Dayang Chem (Hangzhou) Co., Ltd. | Tel: 571-88938639, 8617705817739 | Purity: 95-99%, Package: 0.1KG, 1KG, 1000KG |
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