Hexetidine (CAS 141-94-6) Suppliers and Product Information

Hexetidine is an antibacterial and antifungal agent. It is used as an antimicrobial preservative in cosmetics and non-parenteral pharmaceutical formulations. Therapeutically, it is mainly used as a 0.1% (w/v) solution in mouthwash formulations for the prevention and treatment of minor local infections, gingivitis, and mouth ulcers.

Hexetidine achieves its antibacterial effect by binding to the cell walls of bacteria, impeding the synthesis of new cell walls. This prevents bacterial growth and ultimately leads to their demise.

Frequently Asked Questions about Hexetidine

Q: What are the main uses of Hexetidine?

A: Hexetidine is primarily used as an antibacterial and antifungal agent. It is commonly found in mouthwash formulations for treating minor oral infections, gingivitis, and mouth ulcers. It's also used as an antimicrobial preservative in cosmetics and non-parenteral pharmaceutical products.

Q: Is Hexetidine safe to use?

A: Hexetidine is generally regarded as a relatively non-toxic and non-irritant material at concentrations up to 0.1% (w/v). However, allergic contact dermatitis and altered olfactory and taste perception have occasionally been reported. Long-term toxicological studies of up to 0.1% (w/w) of hexetidine in food for 1 year showed no toxic effects.

Q: How should Hexetidine be stored?

A: Hexetidine should be stored in a well-closed container in a cool, dry place. It's important to note that brass and copper equipment should not be used for handling or storage of hexetidine.

Q: Are there any incompatibilities with Hexetidine?

A: Yes, hexetidine is incompatible with strong oxidizing agents. It forms salts with mineral and organic acids. Strong acids can cause opening of the hexahydropyrimidine ring, releasing formaldehyde.