(1S,2S)-( )-Pseudoephedrine hydrochloride (CAS 345-78-8)

Pseudoephedrine hydrochloride is a sympathomimetic amine used as a nasal decongestant. It is the hydrochloride salt of pseudoephedrine, a phenethylamine and a diastereomer of ephedrine. The compound is subject to control under stimulant regulations in many jurisdictions due to its potential use as a precursor in illicit drug manufacture.

Frequently Asked Questions

Q: What are the main uses of pseudoephedrine hydrochloride?

A: Pseudoephedrine hydrochloride is primarily used as a nasal decongestant in pharmaceutical preparations. It acts as a non-selective adrenergic agonist, helping to relieve nasal congestion.

Q: Are there any safety concerns or drug interactions with pseudoephedrine hydrochloride?

A: Yes, pseudoephedrine hydrochloride can have potentially hazardous interactions with other drugs. It may interact with adrenergic neurone blockers, certain anesthetics, antibacterials like linezolid, and some antidepressants. It's important to consult with a healthcare professional before using this medication, especially if taking other drugs.

Q: How is pseudoephedrine hydrochloride metabolized in the body?

A: Pseudoephedrine hydrochloride is primarily excreted unchanged in the urine. A small amount is hepatically metabolized by N-demethylation. The metabolites are also excreted in the urine.