Bupivacaine Suppliers and Product Information

Bupivacaine is a local anesthetic used for infiltration, spinal, and epidural anesthesia. It is known for its long-lasting action and is commonly used in surgical interventions in urology, lower thoracic surgery, and abdominal surgery. It's also used for blocking nerve transmission in various procedures.

Chemical Properties: - Water Solubility: 101.5mg/L (25°C) - pKa: 8.09 (also reported as 8.17 at 25°C) - Density: 1.0238 (estimate) - Refractive Index: 1.5700 (estimate)

Safety Information: - Hazard Codes: T - Risk Statements: 26/27/28, 38, 41 - Safety Statements: 22, 26, 36/37/39, 45

Frequently Asked Questions about Bupivacaine

Q: What is Bupivacaine? A: Bupivacaine is a potent local anesthetic that blocks nerve impulses, providing temporary numbness in specific areas of the body. It is four times more potent than lidocaine and mepivacaine.

Q: What are the common side effects of Bupivacaine? A: Common side effects include weakness, long-lasting numbness or tingling, restlessness or drowsiness, tremors, headache, blurred vision, fast or slow heartbeats, breathing problems, chills or shivering, back pain, nausea, and vomiting.

Q: How does Bupivacaine work? A: Bupivacaine is a local anesthetic that works by blocking nerve impulses in specific areas of the body. It binds to sodium channels in nerve cells, preventing the propagation of action potentials and thus inhibiting pain sensation.

Q: What is the difference between Bupivacaine and Levobupivacaine? A: Levobupivacaine is the S-enantiomer of Bupivacaine. It is less cardio- and neurotoxic than the racemic mixture (Bupivacaine) while maintaining equivalent potency. Due to its improved safety profile, levobupivacaine is often preferred to reduce the potential for toxicity.