RITODRINE (CAS 26652-09-5) Suppliers and Product Information

Chemical Properties: - Melting point: 88-90°C - Boiling point: 512.3±45.0°C (Predicted) - Density: 1.213±0.06 g/cm³ (Predicted) - pKa: 9.0 (Uncertain)

Description: Ritodrine is a selective β2-adrenoreceptor stimulant predominantly of the urino-genital system. It is used as a tocolytic agent for problems associated with premature miscarriages and only in specialized medical facilities.

Uses: Ritodrine is used as a uterine relaxant and for inhibiting the contractions of premature labor. It is a selective β2 agonist developed specifically for this purpose.

Synthesis: Ritodrine is synthesized from 4-benzyloxypropiophenone through a series of reactions including bromination, reaction with 2-(4-benzyloxyphenyl)ethylamine, and debenzylation using hydrogen with a palladium catalyst.

Frequently Asked Questions about RITODRINE

Q: What is the main use of RITODRINE? A: RITODRINE is primarily used as a tocolytic agent to inhibit premature labor contractions and prevent miscarriages in specialized medical facilities.

Q: How does RITODRINE work? A: RITODRINE is a selective β2-adrenoreceptor stimulant that primarily affects the urino-genital system, relaxing uterine muscles and inhibiting contractions associated with premature labor.

Q: What are the advantages of RITODRINE over non-selective β-agonists? A: RITODRINE has more sustained uterine inhibitory effects and minimal cardiovascular effects compared to non-selective β-agonists, resulting in milder side effects such as mild tachycardia and slight diastolic pressure decrease.

Q: How is RITODRINE typically administered? A: RITODRINE is usually administered initially by intravenous infusion to stop premature labor, and subsequently may be given orally for continued treatment.