Sulfalen (CAS 152-47-6) Suppliers and Product Information

Sulfalen, also known as sulfamethopyrazine, is a sulfonamide antibiotic. It is a long-acting compound with a plasma half-life of 60 hours, allowing for weekly dosing in some applications. The compound has been used in the treatment of urinary tract infections and as a possible antimalarial drug.

Sulfalen can be synthesized through various methods, typically involving reactions with 2-aminopyrazine derivatives and 4-acetylaminobenzenesulfonyl chloride, followed by hydrolysis steps. The compound is part of the sulfonamide class of antibiotics and works by inhibiting bacterial growth.

Frequently Asked Questions about Sulfalen

Q: What is the main use of Sulfalen?

A: Sulfalen is primarily used as an antibiotic, particularly for treating urinary tract infections. It has also been investigated as a potential antimalarial drug.

Q: How is Sulfalen administered?

A: Due to its long half-life, Sulfalen can be administered in a single weekly dose of 2g to maintain adequate blood levels for treatment.

Q: Are there any side effects associated with Sulfalen?

A: Like other long-acting sulfonamides, Sulfalen has been associated with an increased incidence of erythema multiforme. As with all medications, it should be used under medical supervision.

Q: How does Sulfalen work?

A: Sulfalen, as a sulfonamide antibiotic, works by inhibiting bacterial growth. It interferes with the bacteria's ability to synthesize folic acid, which is essential for their survival and reproduction.