Imipramine (CAS 50-49-7) Suppliers and Product Information

Imipramine is a tricyclic antidepressant used to treat depression, enuresis in children, and Parkinson's disease. It acts by inhibiting the reuptake of serotonin and norepinephrine in the central nervous system. The compound appears as a colorless to light yellow liquid or solid, and is soluble in ethanol.

Frequently Asked Questions about Imipramine

Q: What is the main use of Imipramine?

A: Imipramine is primarily used as an antidepressant. It is also used to treat enuresis (bedwetting) in children and symptoms of Parkinson's disease.

Q: How does Imipramine work?

A: Imipramine works by inhibiting the reuptake of serotonin and norepinephrine in the central nervous system, which helps to alleviate symptoms of depression.

Q: What are the common side effects of Imipramine?

A: Common side effects include sedation, drowsiness, dry mouth, urinary retention, constipation, and orthostatic hypotension. These are likely due to its anticholinergic, anti-α adrenergic, and antihistaminergic receptor blocking properties.

Q: Are there any precautions when using Imipramine?

A: Imipramine should not be used with monoamine oxidase inhibitors or treatments that increase catecholamine concentrations. It should be avoided in patients with cardiovascular disease, seizure disorders, or those who may abuse alcohol, as it can lower seizure threshold and produce cardiovascular toxicity.