Iloprost (CAS 78919-13-8) Suppliers and Product Information

Iloprost is a synthetic ***ogue of prostacyclin (PGI2) used to treat pulmonary arterial hypertension, scleroderma, Raynaud's phenomenon, and ischemia. It acts as a vasodilator and inhibits platelet aggregation by binding to prostacyclin receptors and elevating cAMP levels.

Iloprost is soluble in methyl acetate and is light-sensitive. It has a predicted boiling point of 539.2°C at 760 mmHg and a predicted density of 1.21 g/cm3. The compound has a pKa of 4.77.

Frequently Asked Questions

Q: What are the main uses of Iloprost?

A: Iloprost is primarily used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon, and ischemia. It acts as a vasodilator and inhibits platelet aggregation.

Q: How does Iloprost work?

A: Iloprost works by binding to prostacyclin receptors, particularly the IP receptor, which leads to an elevation of cAMP levels. This results in vasodilation and inhibition of platelet aggregation.

Q: What is the typical purity of commercially available Iloprost?

A: Most suppliers offer Iloprost with a purity of 98% or higher.

Q: How should Iloprost be stored?

A: Iloprost should be stored at -20°C and protected from light due to its light-sensitive nature.