Pyrilamine (CAS 91-84-9) Suppliers and Product Information

Pyrilamine, also known as Mepyramine, is an antihistamine used for allergy symptoms and rhinitis. It is an ethylenediamine derivative with one amino nitrogen substituted by two methyl groups and the other by a 4-methoxybenzyl and a pyridin-2-yl group. Pyrilamine works synergistically with diclofenac as a therapeutic alternative for managing inflammatory pain.

Safety Information: Pyrilamine may cause somnolence, central nervous system depression, and gastrointestinal disturbances. Other potential side effects include drowsiness, dry mouth, headache, nausea, tachycardia, and urinary retention. In severe cases, it may lead to hallucinations, stupor, coma, and convulsions.

Reactivity: Pyrilamine neutralizes acids to form salts and water in exothermic reactions. It may be incompatible with isocyanates, halogenated organics, peroxides, phenols, epoxides, anhydrides, and acid halides. It may generate flammable hydrogen gas when combined with strong reducing agents like hydrides.

Frequently Asked Questions about Pyrilamine

Q: What is the main use of Pyrilamine?

A: Pyrilamine is primarily used as an antihistamine to treat allergy symptoms and rhinitis. It also works synergistically with diclofenac for managing inflammatory pain.

Q: Is Pyrilamine water-soluble?

A: Pyrilamine has limited water solubility. Its solubility in water is approximately 3.425g/L at 37.5°C.

Q: What are the potential side effects of Pyrilamine?

A: Common side effects include drowsiness, dry mouth, headache, nausea, and urinary retention. In severe cases, it may cause hallucinations, stupor, coma, and convulsions.

Q: How should Pyrilamine be stored?

A: Pyrilamine may be sensitive to light. It should be stored in a cool, dry place, protected from light and moisture.