Property | Value |
---|---|
CAS Number | 1404-19-9 |
Molecular Formula | C45H74O11 (for Oligomycin A) |
Molecular Weight | 791.06 (for Oligomycin A) |
Appearance | White to pale yellow powder |
Solubility | Soluble in DMSO (up to 300 mg/ml), ethanol (up to 200 mg/ml), acetone. Sparingly soluble in water. |
Storage | Store at -20°C |
Melting Point | 84-100°C |
Oligomycin is a macrolide antibiotic that inhibits mitochondrial ATP synthase. It is a mixture of oligomycins A, B, and C. Oligomycin is used as a tool in biochemical research to inhibit oxidative phosphorylation and decrease cellular ATP levels.
Q: What is the primary mechanism of action of oligomycin?
A: Oligomycin specifically inhibits the mitochondrial F1F0-ATP synthase by binding to the Fo subunit, preventing ATP synthesis and disrupting oxidative phosphorylation.
Q: What are some applications of oligomycin in research?
A: Oligomycin is used as a tool to: - Decrease cellular ATP levels - Induce autophagy - Stimulate lysosome acidification - Study mitochondrial function and energy metabolism - Sensitize cancer cells to certain treatments
Q: How should oligomycin be stored?
A: Oligomycin should be stored at -20°C upon arrival. It is stable for 2 years from the date of purchase when supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Company Name | Contact | Product Details |
---|---|---|
Shenzhen Excellent Biotech Co., Ltd | 13480692018 | Purity: ≥99%, Package: 1KG/5KG/25KG |
Career Henan Chemical Co. | 86 0371 86658258, 8613203830695 | Purity: 98%, Package: 1KG |
Shaanxi Dideu Medichem Co., Ltd | 86 029 89586680, 86 18192503167 | Purity: 99.9%, Package: 25kgs/200kgs Drum, FDA/GMP/CEP Approved |
Xi'an Tianguangyuan Biotech Co., Ltd | 86 029 86333380, 18829239519 | Purity: 99%, Package: 100G/1KG/5KG/25KG, Pharmaceutical grade |
BOC Sciences | 16314854226 | Custom synthesis services available |
This article was written by bob and published on 2024-07-14 02:35:19. Original article, reproduction is prohibited. The content is for entertainment purposes only and should not be taken as fact.
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