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Oligomycin (CAS 1404-19-9) Suppliers and Product Information

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  • 2024-07-14 02:35:19
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PropertyValue
CAS Number1404-19-9
Molecular FormulaC45H74O11 (for Oligomycin A)
Molecular Weight791.06 (for Oligomycin A)
AppearanceWhite to pale yellow powder
SolubilitySoluble in DMSO (up to 300 mg/ml), ethanol (up to 200 mg/ml), acetone. Sparingly soluble in water.
StorageStore at -20°C
Melting Point84-100°C

Oligomycin is a macrolide antibiotic that inhibits mitochondrial ATP synthase. It is a mixture of oligomycins A, B, and C. Oligomycin is used as a tool in biochemical research to inhibit oxidative phosphorylation and decrease cellular ATP levels.

Frequently Asked Questions

2Oligomycin (CAS 1404-19-9) Suppliers and Product Information

Q: What is the primary mechanism of action of oligomycin?

A: Oligomycin specifically inhibits the mitochondrial F1F0-ATP synthase by binding to the Fo subunit, preventing ATP synthesis and disrupting oxidative phosphorylation.

Q: What are some applications of oligomycin in research?

A: Oligomycin is used as a tool to: - Decrease cellular ATP levels - Induce autophagy - Stimulate lysosome acidification - Study mitochondrial function and energy metabolism - Sensitize cancer cells to certain treatments

Q: How should oligomycin be stored?

A: Oligomycin should be stored at -20°C upon arrival. It is stable for 2 years from the date of purchase when supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Company NameContactProduct Details
Shenzhen Excellent Biotech Co., Ltd13480692018Purity: ≥99%, Package: 1KG/5KG/25KG
Career Henan Chemical Co. 86 0371 86658258, 8613203830695Purity: 98%, Package: 1KG
Shaanxi Dideu Medichem Co., Ltd 86 029 89586680, 86 18192503167Purity: 99.9%, Package: 25kgs/200kgs Drum, FDA/GMP/CEP Approved
Xi'an Tianguangyuan Biotech Co., Ltd 86 029 86333380, 18829239519Purity: 99%, Package: 100G/1KG/5KG/25KG, Pharmaceutical grade
BOC Sciences16314854226Custom synthesis services available