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3,5,5-Trimethyloxazolidine-2,4-dione (CAS 127-48-0) Suppliers and Product Information

  • bobbob
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  • 2024-08-02 04:29:04
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PropertyValue
Product Name3,5,5-Trimethyloxazolidine-2,4-dione
CAS Number127-48-0
Molecular FormulaC6H9NO3
Molecular Weight143.14
SynonymsTrimethadione, 3,5,5-Trimethyl-2,4-dioxooxazolidine, 2,4-Oxazolidinedione, 3,5,5-trimethyl-
Melting Point45-46°C
Boiling Point78-80°C (5mm)
AppearanceWhite to Off-White Solid
SolubilitySoluble in water (50 g/L), very soluble in ethanol

3,5,5-Trimethyloxazolidine-2,4-dione, also known as Trimethadione, is an anticonvulsant drug used in the treatment of absence seizures (petit mal epilepsy) that are refractory to other medications. It is a white granular crystalline substance with a camphor-like odor. The compound is soluble in water, alcohol, chloroform, and ether.

23,5,5-Trimethyloxazolidine-2,4-dione (CAS 127-48-0) Suppliers and Product Information

Trimethadione is primarily used as a pharmaceutical intermediate and chemical reagent. It has applications in the control of absence seizures that do not respond to treatment with other drugs. However, due to its potentially severe side effects, including aplastic anemia, nephrosis, and exfoliative dermatitis, its use is now rare.

Frequently Asked Questions

Q: What is the main use of 3,5,5-Trimethyloxazolidine-2,4-dione?

A: 3,5,5-Trimethyloxazolidine-2,4-dione, also known as Trimethadione, is primarily used as an anticonvulsant drug for treating absence seizures (petit mal epilepsy) that are resistant to other medications. It is also used as a pharmaceutical intermediate and chemical reagent.

Q: What are the physical properties of this compound?

A: 3,5,5-Trimethyloxazolidine-2,4-dione is a white to off-white solid with a camphor-like odor. It has a melting point of 45-46°C and a boiling point of 78-80°C at 5mm pressure. It is soluble in water (50 g/L) and very soluble in ethanol.

Q: Are there any safety concerns associated with this compound?

A: Yes, there are significant safety concerns. Trimethadione can have potentially fatal side effects, including aplastic anemia, nephrosis, idiosyncratic rashes, and exfoliative dermatitis. Due to these risks, its use in medical treatment is now rare.

Q: How is 3,5,5-Trimethyloxazolidine-2,4-dione synthesized?

A: The compound is typically synthesized by methylating 5,5-trimethyloxazolidine-2,4-dione with dimethyl sulfate. The starting material, 5,5-trimethyloxazolidine-2,4-dione, is produced by the cyclocondensation of the ester of 2-hydroxyisobutyric acid with urea.

Company NameContactProduct Details
TargetMol Chemicals IncTel: 1 781-999-5354Purity: 100.00%, Package: 100mg, 200mg
HANGZHOU CLAP TECHNOLOGY CO., LTDTel: 86 571 88216897/88216896, 13588875226Purity: 76-89%, Package: 10kg, 25kg, 200kg/barrel
Dideu Industries Group LimitedTel: 86 29 89586680, 86 15129568250Purity: 99.9%, Package: 1g (1.1USD)
Alfa ChemistryTel: 1 5166625404Product Name: Trimethadione
Nantong HI FUTURE Biology Co., LtdTel: 18051384581Purity: 98% (HPLC), Package: 100mg, 500mg, 1g, 5g, 10g
This article was written by bob and published on 2024-08-02 04:29:04. Original article, reproduction is prohibited. The content is for entertainment purposes only and should not be taken as fact.
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