Adefovir (CAS 106941-25-7) Suppliers and Product Information

Adefovir is an antiviral drug used for the treatment of chronic hepatitis B virus infections. It is a nucleotide ***og reverse transcriptase inhibitor that blocks the reproduction of HBV by inhibiting reverse transcriptase in the body. Adefovir is often formulated as the prodrug adefovir dipivoxil for oral administration.

Frequently Asked Questions

Q: What is the main use of Adefovir?

A: Adefovir is primarily used for the treatment of chronic hepatitis B virus (HBV) infections. It is effective in inhibiting HBV DNA polymerase (reverse transcriptase), thereby blocking the reproduction of the virus.

Q: How does Adefovir compare to other HBV treatments?

A: One advantage of Adefovir over another anti-HBV drug, lamivudine, is that it is much harder for the virus to develop resistance to it. This makes Adefovir a valuable option for long-term HBV treatment.

Q: What are the common side effects of Adefovir?

A: Adefovir is generally well-tolerated. The most common side effects include headache, pharyngitis, abdominal pain, and peripheral neuropathy. In some cases, nephrotoxicity has been observed, particularly in patients receiving higher doses or longer courses of therapy.

Q: Is Adefovir effective against HIV?

A: While Adefovir was initially studied for its potential against HIV, it has been found to show no effect against HIV-1. Its primary clinical use is for the treatment of hepatitis B virus infections.