Latamoxef Sodium (CAS 64953-12-4) Suppliers and Product Information

Latamoxef sodium is an oxacephem antibiotic synthesized by Shionogi Pharmaceuticals in 1975. It has strong activity against gram-negative bacteria, high resistance to β-lactamase action, and excellent activity against Pseudomonas aeruginosa. However, it has no activity against Staphylococcus aureus. It is more effective against Escherichia coli and Pseudomonas aeruginosa than cephalosporins.

The compound acts as a bacterial transpeptidase inhibitor and interferes with cell wall synthesis. It is unstable in solution (DMSO or Methanol) and should be stored under inert atmosphere at 2-8°C.

Frequently Asked Questions about Latamoxef Sodium

Q: What is the main use of Latamoxef sodium?

A: Latamoxef sodium is primarily used as an antibiotic. It is particularly effective against gram-negative bacteria and shows excellent activity against Pseudomonas aeruginosa.

Q: How does Latamoxef sodium work?

A: Latamoxef sodium works by inhibiting bacterial cell wall synthesis. It acts as a bacterial transpeptidase inhibitor, which interferes with the formation of peptidoglycan cross-links in the bacterial cell wall.

Q: Are there any safety concerns with Latamoxef sodium?

A: Yes, there are some safety concerns. Latamoxef sodium has been associated with impaired normal hemostasis and prolonged bleeding time in certain situations. It's important to use this medication under proper medical supervision.

Q: How should Latamoxef sodium be stored?

A: Latamoxef sodium should be stored under inert atmosphere at 2-8°C. It is unstable in solution (DMSO or Methanol), so proper storage is crucial to maintain its efficacy.